The General Manuscripts Collection is largely composed of materials related to United States politics and government, including personal and business correspondence, manuscripts, memorabilia, pamphlets, and reports. The collection includes the papers of many individuals, including Franklin Delano Roosevelt, Theodore Roosevelt and other United States presidents, government officials, authors and journalists, bankers and businessmen, and Princeton University alumni.

The Records of United Service to China, Inc., known from 1941 to 1946 as United China Relief, Inc., document the activities of the organization from the early formation in 1940 to its official consolidation with the American Bureau for Medical Aid to China in 1966. In addition there is a limited amount of material from other Chinese relief agencies that predate the founding of United China Relief / United Service to China. The Records focus on UCR/USC attempts to raise money in the United States, to educate Americans about China and the Chinese people, and to carry on relief work in China. The collection consists primarily of correspondence among the various individuals and agencies involved with UCR/USC, along with other material produced by the agency, such as minutes and publicity material. In addition, the collection includes a series of photographs dealing with China during the 1940s and efforts in the United States to raise money for China during the same period.

A. Frederick Gerstell is a member of the Princeton University Class of 1960. The collection is composed of mostly World War II-era correspondence, photographs, and ephemera collected by Gerstell.

This collection consists of essays, notes on readings, laboratory notebooks, drawings and similar academic work products created by Princeton students.

The Department of Chemistry at Princeton University dates back to the early days of the College of New Jersey, and today it is one of the University's largest undergraduate concentrations. The collection contains examinations and grade books, records pertaining to chemistry research performed at the department in support of the U.S. Manhattan project and departmental records.

The Princeton Nassoons are a close-harmony, all male, student a cappella group that formed in the late 1930s. The collection consists primarily of the Princeton Nassoons' original musical arrangements and correspondence.

The L. Ashton Sly Collection of Musical Scores is a 137 volume collection of vocal scores and/or libretti for one hundred twenty-three musical comedies, comic operas, and operettas, including twenty-eight full production promptbooks. These are arranged alphabetically by title and housed in 8 record center cartons.

Princeton University's School of Engineering and Applied Science is an academic unit which since 1921 has overseen the curriculum and administration of the University's academic departments in the engineering sciences. The records document the activities of the School of Engineering and its subordinate departments and programs from its origins in the late 19th century until the present, and consist of correspondence, subject files, research reports, photographs, and other audiovisual materials.

Consists of a closed collection of more than 5,000 Western Americana photographs, consisting mostly of documentary photographs of the Trans-Mississippi West from the late 1860s to early 1900s, largely from the perspective of white photographers and settlers. Subjects include American Indians (especially studio portraits), natural wonders, cities, towns, buildings, and economic activities (mining, railroads, logging, and agriculture). Some photographs relate to the Indigenous populations of Mexico and Central America. The dimensions, physical formats, and photographic processes of the photographs vary widely.

Consists of manuscripts, correspondence, and documents of Walter Livingston Wright, Jr. (Princeton Class of 1921) relating to his work in Turkey, Princeton, and Washington, D.C., as well as papers of his father, Walter Livingston Wright (Class of 1892) who was president of Lincoln University (Pa.).