The Scholarship series contains materials related to Lotka's writings, including articles, speeches, and lectures. The majority of the papers are composed of Lotka's notes and articles he collected about a variety of subjects. The papers also include drafts of articles and speeches, data tables, clippings, correspondence, and offprints of his articles. The series includes materials related to his publications Elements of Physical Biology and Theorie Analytique des Associations Biologiques. The series also includes Lotka's correspondence with Robert R. Kuczynski and Vito Volterra regarding their interpretation of Lotka's works in their writings.

The Oversized Materials series contains glass slides used by Lotka for visual aids during a lecture, a scrapbook of Lotka's writings, charts and graphs, a certificate of membership for the Committee on Medicine and Public Health for the 1939 New York World's Fair, and panoramic photographs of groups at Metropolitan Life Insurance Company events and delegates to the Eighth American Scientific Congress.

Series 1, Correspondence, 1942-1968, is arranged chronologically, and consists primarily of carbon copies of letters Trimble sent, though there are some letters that he received. As he rose in rank, the volume of correspondence increases. Each posting created a different range of correspondents and concerns. In general, Trimble's correspondence is routine in nature. Primarily in English, some correspondence is in the local language of the country in which he served, specifically Spanish, Portuguese, German and French.

Series 2, Speeches and Writings, 1937-1968, is arranged chronologically and consists primarily of speeches delivered by Trimble as part of his duties. Many of them are written in the local language, i.e. German for his time in Germany and French for his time in Cambodia. A majority of the speeches are routine in nature with such subjects as the celebration of American holidays abroad, dedication ceremonies, and speeches delivered to organizations, such as the National War College.

Series 3, General Subject Files, 1940-1968, is arranged alphabetically primarily by Trimble's service location and then by subject. The subjects covered by these files include statistical data on Africa in the mid-1960s, a personal diary from 1958 while in Germany, material relating to Vice President Nixon's visit to Brazil in 1956, notes on his time in Cambodia, and a copy of a lecture given at the National War College by George Kennan ("Structure of Internal Power in U.S.S.R."). Box 18 of the collection contains oversized items related to this series.