The Lorenzo García Vega Papers consists of manuscript first drafts (see Notebooks), one handwritten manuscript of Palíndromo en otra cerradura: Homenaje a Duchamp, a computer printout of "Cuaderno del Bagboy" and computer printout of Devastación del Hotel San Luis with corrections by the Argentine writer Héctor Libertella. Of significance to this collection are twenty-nine notebooks in which García Vega recorded daily diary entries, ideas, drafts of poems, stories and correspondence, fragments of poems and stories, recollections of dreams, quotations, and responses to literature and art. In many cases it appears that García Vega reused notebooks of his spouse or child, writing on top of or around another person's notations. Most of the notebooks are undated, and yet some may date into the 2000s, with content possibly related to García Vega's newspaper columns, also included in the collection.

The correspondence in the collection includes letters received by García Vega, dating from 1969 until 1996, though undated letters from Héctor Libertella regarding the manuscript of Devastación del Hotel San Luis [2007] may date into the 2000s. Most notable are multiple letters from Guido Llinás, Octavio Paz, and Manuel Díaz Martínez.

The collection also contains newspaper clippings of articles by García Vega for the Miami newspaper "El Nuevo Herald" and clippings of articles about García Vega.